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Top 23 Python Python Projects
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system-design-primer
Learn how to design large-scale systems. Prep for the system design interview. Includes Anki flashcards.
Project mention: The One GitHub Repository Every System Design Learner Should Bookmark | dev.to | 2026-06-15Repository: https://github.com/donnemartin/system-design-primer
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Project mention: Stop Hoarding Junk Code! Your Algorithm Learning Bible Awaits | dev.to | 2025-09-01
git clone https://github.com/TheAlgorithms/Python.git cd Python
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AutoGPT
AutoGPT is the vision of accessible AI for everyone, to use and to build on. Our mission is to provide the tools, so that you can focus on what matters.
AutoGPT (agpt.co): Open-source autonomous agent framework, released in 2023. Pioneering example of general-purpose agent architecture; known for demonstrating both promise and limitations of autonomous systems.
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Pro-tip: yt-dlp works great with TikTok, so you don’t have to actually open the page if you still wanna view the video.
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Link (Github): https://github.com/AUTOMATIC1111/stable-diffusion-webui
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transformers
🤗 Transformers: the model-definition framework for state-of-the-art machine learning models in text, vision, audio, and multimodal models, for both inference and training.
Project mention: The $100 ChatGPT: Why Karpathy's nanochat Represnts the Next Big Thing | dev.to | 2026-05-04Hugging Face Transformers: 500,000+ lines
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HelloGitHub
:octocat: 分享 GitHub 上有趣、入门级的开源项目。Share interesting, entry-level open source projects on GitHub.
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Project mention: How to Use an AI Agent — Build a Working Agent Team in Three Steps | dev.to | 2026-06-12
How do you use an AI Agent? Three steps: pick a platform → define the Agent → run and iterate. The core formula — define the role, set the goal, connect the tools, draw the red lines. Developers build with LangChain; non-technical teams drag and drop on SoloEngine. You can have an Agent up and running in 5 minutes. Tech isn't the barrier — clearly defining your Agent is.
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ComfyUI
The most powerful and modular diffusion model GUI, api and backend with a graph/nodes interface.
So I use a combination of Neo Forge and ComfyUI. Forge has an easier learning curve but ComfyUI gets all the new "hotness" almost immediately since there's so much custom nodes for it.
If you're on a Mac, I've heard that Draw Things is supposed to be pretty "batteries included" simple for image gen along the same lines as LM Studio.
https://github.com/Haoming02/sd-webui-forge-classic/tree/neo
https://github.com/Comfy-Org/ComfyUI
https://drawthings.ai
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Explore the repository and contribute to the future of AI: https://github.com/Shubhamsaboo/awesome-llm-apps
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Project mention: Tracing torch.cuda.empty_cache() on an RTX 4090 - Where Do the 53 MB Go? | dev.to | 2026-05-28
pytorch/pytorch#173382 - a user calls torch.cuda.empty_cache() after deleting tensors, but GPU memory stays allocated. The caching allocator's empty_cache() only releases blocks it has marked as free, but the user sees a persistent gap between "allocated" and "reserved" memory. We traced what happens when torch cuda empty cache runs on an RTX 4090 and measured exactly how much GPU memory it reclaims.
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browser-use
Open-source browser automation framework for AI agents. Browser Use lets AI agents control real browser sessions to complete multi-step web workflows.
browser-use: https://github.com/browser-use/browser-use
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Project mention: Show HN: A faster fuck (thefuck CLI rewritten in Rust) | news.ycombinator.com | 2026-02-26
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Project mention: 3..2..1 Launch!: My journey from zero to Django Contributions | dev.to | 2026-05-15
PR: Link This is very interesting bug. You can perform coalesce to receive not-null first value from given columns fetching. However, column's type are vary. Let imagine you coalesce Column A (string), Column B (JSON).
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Home Assistant
:house_with_garden: Open source home automation that puts local control and privacy first.
https://www.home-assistant.io/
the interface can be set up on her phone, a tablet on a wall, and limiting things to giant buttons and displays is very easy for you.
And, you can monitor and be alerted near real time to issues of course.
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git clone https://github.com/harry0703/MoneyPrinterTurbo.git cd MoneyPrinterTurbo docker-compose up # WebUI: localhost:8501, API: localhost:8080
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Wow, it's actually real.
https://old.reddit.com/r/github/comments/1at9br4/i_am_new_to...
https://github.com/sherlock-project/sherlock/issues/2011
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devops-exercises
Linux, Jenkins, AWS, SRE, Prometheus, Docker, Python, Ansible, Git, Kubernetes, Terraform, OpenStack, SQL, NoSQL, Azure, GCP, DNS, Elastic, Network, Virtualization. DevOps Interview Questions
Project mention: 10 GitHub Repositories That Will Actually Teach You DevOps in 2026 | dev.to | 2026-05-05github.com/bregman-arie/devops-exercises. 82k stars. Maintained by Arie Bregman, ex-Red Hat.
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Flask
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deer-flow
An open-source long-horizon SuperAgent harness that researches, codes, and creates. With the help of sandboxes, memories, tools, skill, subagents and message gateway, it handles different levels of tasks that could take minutes to hours.
Tools have been trending in this direction for the last 3-6 months with features like "Assign to Copilot" in GitHub.com, and the Linear's work tracking system where its unique sales pitch is "write tickets for agents to work on here". The final form of this kind of solution is currently a vague, but there are several projects already pitching to own this space such as Open AI's Symphony project (https://openai.com/index/open-source-codex-orchestration-symphony/), ByteDance's DeerFlow (https://github.com/bytedance/deer-flow) which pitches itself as "an open-source super-agent harness", and other similar projects.
Python Python discussion
Python Python related posts
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Microsoft turns to AWS as GitHub faces AI capacity crunch
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Python 3.14 garbage collection rigamarole
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Pyinfra – agentless infrastructure automation, in plain Python
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Fine Tune Llama 3 For Sql Query Generation Tutorial
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Show HN: Manim-Studio – Prompt to 3blue1brown video
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AI agent on GitHub gives recipe for blueberry pie
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How I Fixed Bugs in 30+ Open Source Projects (And What I Learned)
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A note from our sponsor - SaaSHub
www.saashub.com | 15 Jun 2026
Index
What are some of the best open-source Python projects in Python? This list will help you:
| # | Project | Stars |
|---|---|---|
| 1 | system-design-primer | 352,602 |
| 2 | awesome-python | 302,340 |
| 3 | TheAlgorithms | 221,910 |
| 4 | AutoGPT | 184,885 |
| 5 | yt-dlp | 170,274 |
| 6 | stable-diffusion-webui | 163,629 |
| 7 | transformers | 161,558 |
| 8 | HelloGitHub | 160,893 |
| 9 | langchain | 139,168 |
| 10 | ComfyUI | 116,497 |
| 11 | awesome-llm-apps | 114,288 |
| 12 | Pytorch | 100,659 |
| 13 | fastapi | 99,095 |
| 14 | browser-use | 98,375 |
| 15 | thefuck | 96,569 |
| 16 | Django | 87,845 |
| 17 | Home Assistant | 87,648 |
| 18 | manim | 87,556 |
| 19 | MoneyPrinterTurbo | 87,208 |
| 20 | sherlock | 84,944 |
| 21 | devops-exercises | 82,703 |
| 22 | Flask | 71,636 |
| 23 | deer-flow | 70,969 |