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Top 23 Python TypeScript Projects
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deer-flow
An open-source long-horizon SuperAgent harness that researches, codes, and creates. With the help of sandboxes, memories, tools, skill, subagents and message gateway, it handles different levels of tasks that could take minutes to hours.
Tools have been trending in this direction for the last 3-6 months with features like "Assign to Copilot" in GitHub.com, and the Linear's work tracking system where its unique sales pitch is "write tickets for agents to work on here". The final form of this kind of solution is currently a vague, but there are several projects already pitching to own this space such as Open AI's Symphony project (https://openai.com/index/open-source-codex-orchestration-symphony/), ByteDance's DeerFlow (https://github.com/bytedance/deer-flow) which pitches itself as "an open-source super-agent harness", and other similar projects.
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SaaSHub
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quivr
Opiniated RAG for integrating GenAI in your apps 🧠 Focus on your product rather than the RAG. Easy integration in existing products with customisation! Any LLM: GPT4, Groq, Llama. Any Vectorstore: PGVector, Faiss. Any Files. Anyway you want.
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PostHog
🦔 PostHog is an all-in-one developer platform for building successful products. We offer product analytics, web analytics, session replay, error tracking, feature flags, experimentation, surveys, data warehouse, a CDP, and an AI product assistant to help debug your code, ship features faster, and keep all your usage and customer data in one stack.
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Project mention: One Open Source Project per Day #74: ai-engineering-from-scratch - Build AI Full-stack Skills from Ground Up | dev.to | 2026-05-23
git clone https://github.com/rohitg00/ai-engineering-from-scratch.git cd ai-engineering-from-scratch python phases/01-math-foundations/01-linear-algebra-intuition/code/vectors.py
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Then in November, I got inspired from laramap and launched Indiemap for Indie-hackers & solo-founders. It was one map to gather all indie-hackers to connect with same builder same city from worldwide. Currently, I have 70+ indie-hackers there. I done build in public marketing for almost 2 months, then I took break due to family function and due to wedding season. I integrated payment gateway to monetize it with popular polar.sh for indie builders.
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agent-squad
Flexible and powerful framework for managing multiple AI agents and handling complex conversations
Project mention: Orchestrating Multi-Agents: Unifying Fragmented Tools into Coordinated Workflows | dev.to | 2025-06-29AWS Agent Squad (GitHub)
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DeepAudit
DeepAudit:人人拥有的 AI 黑客战队,让漏洞挖掘触手可及。国内首个开源的代码漏洞挖掘多智能体系统。小白一键部署运行,自主协作审计 + 自动化沙箱 PoC 验证。支持 Ollama 私有部署 ,一键生成报告。支持中转站。让安全不再昂贵,让审计不再复杂。
Project mention: Show HN: DeepAudit – open-source auditing agent (LLMs and Static Analysis) | news.ycombinator.com | 2025-12-15 -
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git clone https://github.com/plastic-labs/honcho cd honcho docker compose up -d # Server will be on http://localhost:8000
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fastapi-react
🚀 Cookiecutter Template for FastAPI + React Projects. Using PostgreSQL, SQLAlchemy, and Docker
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cascadeflow
Cascading runtime for AI agents. Optimize cost, latency, quality, and policy decisions inside the agent loop.
Project mention: Why One Model Is Never Enough: Routing Incident Analysis With cascadeflow | dev.to | 2026-05-22This is the story of how I built IncidentOS, an AI-powered operational memory system for SRE teams, and why cascadeflow became the piece that made the runtime actually usable.
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If you've used E2B, Daytona, Modal sandboxes, or Cloudflare Sandboxes, the shape is familiar: REST API, Python and JS SDKs, exec / files / snapshot primitives. Here's what the Python SDK looks like:
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instill-core
🔮 Instill Core is a full-stack AI infrastructure tool for data, model and pipeline orchestration, designed to streamline every aspect of building versatile AI-first applications
Project mention: Revolutionizing Unstructured Data: Instill Core – Your All-in-One AI Solution | dev.to | 2025-07-14View the Project on GitHub
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arl
lists of most popular repositories for most favoured programming languages (according to StackOverflow)
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agent-protocol
Common interface for interacting with AI agents. The protocol is tech stack agnostic - you can use it with any framework for building agents.
Python TypeScript discussion
Python TypeScript related posts
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PostHog Custom Surveys: Beyond the Default UI
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Show HN: See you speaker's output on a piano
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Persistent Memory for OpenClaw on Bedrock: Getting Prompt Caching Right
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What Is Web3 User Analytics? A Complete Guide to Driving Growth
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Building an ML-Powered Notification Router on AWS: A Production Architecture Guide
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Apogee Watcher vs PostHog Web Vitals: Synthetic PageSpeed Monitoring and Product Analytics Compared
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Why You Probably Don't Need a Full-Time CTO
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A note from our sponsor - SaaSHub
www.saashub.com | 14 Jun 2026
Index
What are some of the best open-source TypeScript projects in Python? This list will help you:
| # | Project | Stars |
|---|---|---|
| 1 | deer-flow | 70,969 |
| 2 | quivr | 39,155 |
| 3 | PostHog | 35,010 |
| 4 | ai-engineering-from-scratch | 13,774 |
| 5 | E2B | 12,558 |
| 6 | polar | 9,932 |
| 7 | agent-squad | 7,652 |
| 8 | oppia | 6,713 |
| 9 | DeepAudit | 6,378 |
| 10 | basic-pitch | 5,148 |
| 11 | honcho | 5,112 |
| 12 | wave | 4,241 |
| 13 | beeai-framework | 3,288 |
| 14 | fastapi-react | 2,578 |
| 15 | cascadeflow | 2,495 |
| 16 | code-interpreter | 2,340 |
| 17 | instill-core | 2,314 |
| 18 | django-react-boilerplate | 2,262 |
| 19 | arl | 2,084 |
| 20 | Obsidian_to_Anki | 1,942 |
| 21 | lotus | 1,827 |
| 22 | mirascope | 1,493 |
| 23 | agent-protocol | 1,458 |